BDBM50029600 5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene::5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)thiophene::CHEMBL42485::DUP-697
SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1
InChI Key InChIKey=AJFTZWGGHJXZOB-UHFFFAOYSA-N
Data 42 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50029600
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against human COX-1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibitory activity against human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 1 expressed in microsomes taken from baculovirus infected Sf...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 was measured by the inhibition of PGE-2 produced by microsomes from U937 cells at subsaturating arachidoni...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Compound was evaluated for inhibitory activity against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheepMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 41.6nMAssay Description:Inhibition of ovine COX1 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human COX-1 preincubated for 15 mins followed by fluorometric substrate/heme addition for 15 mins subsequently incubated with arachidon...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of COX1 in human platelet microsomes assessed as reduction in formation of oxidized TMPD using arachidonic acid as substrate preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair